US CDC panel votes to advocate mRNA COVID-19 vaccines over J&J’s

The US had briefly paused use of the COVID jab in April, earlier than discovering profit outweighs very uncommon, however lethal, dangers.

A panel of out of doors advisers to the US Centers for Disease Control and Prevention (CDC) has voted to advocate Americans select to obtain one of many different two authorised COVID-19 vaccines over Johnson & Johnson’s shot, as a consequence of uncommon however generally deadly instances of blood clotting.

The CDC’s Advisory Committee on Immunization voted unanimously on Thursday to make the advice. The regulator nonetheless must log out on the steerage.

Fewer Americans have acquired the J&J shot than the opposite two vaccines by a major margin. Out of greater than 200 million absolutely vaccinated individuals within the United States, round 16 million acquired J&J’s vaccine, in keeping with CDC knowledge.

Cases of thrombosis with thrombocytopenia syndrome (TTS), which includes blood clots accompanied by a low stage of platelets, have beforehand been reported in recipients of the J&J vaccine. The highest reporting charges are in ladies underneath 50.

The CDC stated that the speed of such incidents is increased than beforehand estimated, each in ladies and men. The company has recognized greater than 50 instances of TTS within the US, about 3.83 instances per million J&J doses administered.

At least 9 individuals have died following the blood clotting incidents within the US, the CDC has stated.

Members of the panel additionally stated J&J’s vaccine is much less efficient in stopping COVID-19 than the opposite two authorised vaccines.

In a presentation to the committee, a number one J&J vaccine scientist stated the vaccine generates a robust and long-lasting immune response with only a single shot.

“In the setting where many people do not return for a second dose or a booster, the durability of the single shot Johnson & Johnson vaccine as a primary regimen could make a crucial difference in saving lives in the US and around the globe,” J&J’s Dr Penny Heaton stated.

In the US, the shot has been helpful for getting vaccines out to some hard-to-reach populations and settings just like the homeless and residents of corrections amenities.

J&J’s vaccine makes use of a expertise based mostly on a modified model of an adenovirus to spur immunity in recipients, whereas the opposite two authorised vaccines use messenger RNA expertise.

J&J’s one-dose vaccine acquired emergency use authorisation in late February. In April, US regulators paused administering the vaccine for 10 days with a view to examine the blood clotting.

A CDC scientist stated on Thursday that the speed of deaths from TTS didn’t lower after the pause in April.

J&J shares closed up round 1 p.c on the New York Stock Exchange. The firm sells the vaccine at a not-for-profit worth, so it has not been a major income driver.

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